RLCP 1.13.11100.261 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.13.-.- : Amide bond (One of Carbonyl Ester bonds; including peptide bond) (Ligand group involved)

C 1.13.11100.- : Serralysin-like mechanism (Acid-Base/Stabilizer); Cofactor-assisted water activated by base; Cofactor-assisted stabilization of transition-state; Protonation to leaving group by acid; SN1/SN2 unclear (Catalytic mechanism)

P 1.13.11100.261 : Glu/Tyr + zinc ion bound to His cluster (Residues/cofactors in Protein)


1st Nucleophile : water
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There are 2 entries in this class.
  • S00394 : 3.4.24.21; Astacin (Catalytic domain; 3.40.390.10)
  • D00236 : 3.4.24.40; Serralysin (Catalytic domain; 3.40.390.10)