RLCP 1.13.11100.561 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.13.-.- : Amide bond (One of Carbonyl Ester bonds; including peptide bond) (Ligand group involved)

C 1.13.11100.- : Serralysin-like mechanism (Acid-Base/Stabilizer); Cofactor-assisted water activated by base; Cofactor-assisted stabilization of transition-state; Protonation to leaving group by acid; SN1/SN2 unclear (Catalytic mechanism)

P 1.13.11100.561 : Glu/Gln + mainchain amide + Fe(II) bound to Cys/His/His (Residues/cofactors in Protein)

1st Nucleophile : water
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • S00442 :; Peptide deformylase (Catalytic domain;