RLCP 1.14.10105.1251 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.14.-.- : Thioester (One of Carbonyl Ester bonds) (Ligand group involved)

C 1.14.10105.- : Glyoxalase-II-like mechanism (Modulator); Inorganic cofactor-assisted water activation; Inorganic cofactor-assisted stabilization of transition-state; Inorganic-cofactor interaction with water/intermediate (atom adjacent to scissile bond) (Catalytic mechanism)

P 1.14.10105.1251 : Asp + two zinc ions bound to His/Asp cluster (Residues/cofactors in Protein)


1st Nucleophile : water
Catalytic groups : cofactor + groups in residue/substrate
General Base : non-existent
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • S00431 : 3.1.2.6; Hydroxyacylglutathione hydrolase (Catalytic domain; 3.60.15.10)