RLCP 1.15.30200.84 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.15.-.- : Phosphoric Ester (Ligand group involved)

C 1.15.30200.- : Prostatic acid phosphatase-like mechanism (Nucleophile/Acid-Base/Stabilizer); double-displacement; covalent bond formation between nucleophile and target atom; intermediate stablilized; protonation to 1st leaving group by acid; covalent bond attacked by base-activated water; intermediate stabilized; protonation to nucleophile (Catalytic mechanism)

P 1.15.30200.84 : His/Asp + Arg/His cluster (Residues/cofactors in Protein)


1st Nucleophile : a catalytic residue
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There are 2 entries in this class.
  • S00363 : 3.1.3.2; Prostatic acid phosphatase (Catalytic domain; 3.40.50.1240)
  • D00514 : 3.1.3.2, 3.1.3.26; Periplasmic appA protein (Catalytic domain; 3.40.50.1240)