RLCP 1.15.8310.1250 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.15.-.- : Phosphoric Ester (Ligand group involved)

C 1.15.8310.- : Phosphotriesterase-like mechanism (Base); Inorganic-cofactor-assisted activation of scissile bond; Inorganic-cofactor-assisted water activation by base; SN2-like nucleophilic attack by water; Inorganic-cofactor-assisted stabilization of transition-state (Catalytic mechanism)

P 1.15.8310.1250 : An acidic residue + two zinc ions bound to carbamated Lys & His/Asp cluster (Residues/cofactors in Protein)


1st Nucleophile : water
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • S00231 : 3.1.8.1; Parathion hydrolase (Catalytic domain; 3.20.20.140)