RLCP 1.20.30810.950 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.20.-.- : Halide bond (Ligand group involved)

C 1.20.30810.- : Halogenase-like mechanism (Nucleophile/Base/Modulator/Stabilizers); Nucleophilic attack on target bond; Stabilizer for leaving group assists SN2-like reaction; covalent bond between enzyme and substrate (intermediate formation); hydrolysis by base-activated water; intermediate-2; intermediate-2 deformation & hydroxyl group from water protonates to leaving atom (Catalytic mechanism)

P 1.20.30810.950 : Asp/His/Asp + mainchain amide + Trp/Trp (Residues/cofactors in Protein)


1st Nucleophile : a catalytic residue
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent



Related Enzymes

There is one entry in this class.
  • S00356 : 3.8.1.5; Haloalkane dehalogenase (Catalytic domain; 3.40.50.1820)