RLCP 1.20.30810.951 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.20.-.- : Halide bond (Ligand group involved)

C 1.20.30810.- : Halogenase-like mechanism (Nucleophile/Base/Modulator/Stabilizers); Nucleophilic attack on target bond; Stabilizer for leaving group assists SN2-like reaction; covalent bond between enzyme and substrate (intermediate formation); hydrolysis by base-activated water; intermediate-2; intermediate-2 deformation & hydroxyl group from water protonates to leaving atom (Catalytic mechanism)

P 1.20.30810.951 : Asp/His/Glu + mainchain amide + Trp/Asn (Residues/cofactors in Protein)

1st Nucleophile : a catalytic residue
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • S00525 :; Haloalkane dehalogenase (Catalytic domain;