RLCP 1.30.5050.991 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.30.-.- : C-O bond (O-glycoside bond) (Ligand group involved)

C 1.30.5050.- : Cellulase9A-like mechanism (Acid/Base/Modulator); Modulator-assisted base activation; SN1-like intermediate formation induced by protonation to leaving group; water activated by general base attacks on intermediate to complete reaction (Catalytic mechanism)

P 1.30.5050.991 : Three acidic residues + Tyr/His (Residues/cofactors in Protein)


1st Nucleophile : water
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There are 4 entries in this class.
  • S00531 : 3.2.1.4; Endo-b-1,4-glucanase (Cellulase NtEG) (Catalytic domain; 1.50.10.10)
  • D00167 : 3.2.1.4; Cellulase Cel9-M (Catalytic domain; 1.50.10.10)
  • T00246 : 3.2.1.4; Endoglucanase G (Catalytic domain; 1.50.10.10)
  • M00192 : 3.2.1.4; Endoglucanase E-4 (Catalytic domain; 1.50.10.10)