EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.51.-.- : C-C bond (Ketonic Carbon-Carbon bond; Carbonyl Carbon-Carbon adjacent to sp2 carbon) (Ligand group involved)

C 1.51.3100.- : C-C hydrolase-like hydrolysis mechanism (Base/Stabilizer/Modulator); Base activation of water; Activated water attacks on scissile bond; Intermediate stabilized; Bond cleavage occurs (Catalytic mechanism)

P 1.51.3100.78 : His/Ser/Asp (Residues/cofactors in Protein)


1st Nucleophile : water
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There are 2 entries in this class.
  • S00355 : (reaction 2) 3.7.1.8; 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (Catalytic domain; 3.40.50.1820)
  • S00526 : (reaction 2) 3.7.1.-; 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase (Catalytic domain; 3.40.50.1820)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)