RLCP 1.51.790.101 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 1.-.-.- : Hydrolysis (bond cleavage by water) (Reaction)

L 1.51.-.- : C-C bond (Ketonic Carbon-Carbon bond; Carbonyl Carbon-Carbon adjacent to sp2 carbon) (Ligand group involved)

C 1.51.790.- : Beta-ketoacyl-ACP synthase II 2nd reaction step-like mechanism (Base/Stabilizer/Modulator); Modulation of nucleophile; Base deprotonation of nucleophile through a proton-shuttle residue; Nucleophilic attacks on transferred group forming an intermediate; Stabilization of intermediate; Acid protonation to leaving group (SN2-like reaction) (Catalytic mechanism)

P 1.51.790.101 : His/His/Lys (Residues/cofactors in Protein)

1st Nucleophile : water
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • D00871 : (reaction 2); 3-oxoacyl-[acyl-carrier-protein] synthase 2 (Catalytic domain;