EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 2.-.-.- : Phosphorolysis (bond cleavage by phosphate) (Reaction)

L 2.40.-.- : C-N bond (N-glycoside bond) (Ligand group involved)

C 2.40.18000.- : Acid/Stabilizer; SN1-like transition state; nucleophilic attack by phosphate group; Protonation to leaving group by acid (Catalytic mechanism)

P 2.40.18000.65 : Asp + negatively charged residues (Residues/cofactors in Protein)


1st Nucleophile : phosphate group
Catalytic groups : groups in residue/substrate
General Base : non-existent
General Acid : a catalytic residue

Related Enzymes

There are 2 entries in this class.
  • S00376 : 2.4.2.28; S-methyl-5''-thioadenosine phosphorylase (Catalytic domain; 3.40.50.1580)
  • S00510 : 2.4.2.1; Purine nucleoside phosphorylase deoD-type (Catalytic domain; 3.40.50.1580)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)