RLCP 3.103.130000.1161 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.103.-.- : Phosphate group from Phosphate oxygen to Hydroxyl oxygen (Ligand group involved)

C 3.103.130000.- : Insulin receptor-like mechanism (Base/Modulator); Inorganic-cofactor-assisted SN1-like transition state between acceptor/transferred/leaving groups; Base deprotonation of acceptor group; Covalent bond formed between acceptor and transferred group; Inorganic-cofactor interacting with transferred/leaving groups (Catalytic mechanism)

P 3.103.130000.1161 : Asp/Lys + two magnesium ions bound to Asp/Asn (Residues/cofactors in Protein)

1st Nucleophile : an acceptor group in substrate
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There are 2 entries in this class.
  • T00224 :; TGF-beta receptor type-1 (Catalytic domain; 1.10.510.10)
  • M00125 :; Beta-adrenergic receptor kinase 1 (Catalytic domain; 1.10.510.10)