RLCP 3.103.90021.1120 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.103.-.- : Phosphate group from Phosphate oxygen to Hydroxyl oxygen (Ligand group involved)

C 3.103.90021.- : Reverse transcriptase-like mechanism (Stabilizer); Inorganic-cofactor-assisted nucleophilic attack by acceptor group on transferred group; SN2-like direct reaction; Transition state stabilized by cofactor; Inorganic-cofactor interacting with acceptor/transferred/leaving groups & Stabilization of leaving group (Catalytic mechanism)

P 3.103.90021.1120 : mainchain amide groups + two magnesium ions bound to acidic residues (Residues/cofactors in Protein)


1st Nucleophile : an acceptor group in substrate
Catalytic groups : cofactor + groups in residue/substrate
General Base : non-existent
General Acid : non-existent

Related Enzymes

There are 2 entries in this class.
  • M00135 : (reaction 1) 2.7.7.49, 3.1.26.4, 3.4.23.-; Gag-Pol polyprotein (Catalytic domains; 3.30.70.270, 3.30.420.10)
  • M00166 : (reaction 2) 2.7.7.7, 2.7.7.49, 3.1.26.4, 3.4.23.47; Gag-Pol polyprotein (Catalytic domains; 2.40.70.10, 3.30.70.270, 3.30.420.10)