EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.1143.-.- : Acyl group from Phosphate oxygen to Amine nitrogen (sp3) (Ligand group involved)

C 3.1143.50000.- : Aspartate--ammonia ligase acyl transfer mechanism (Base-Stabilizer/Stabilizer); SN1-like reaction; Nucleophilic attack on transferred group by acceptor group; Stabilization of transferred group and acceptor group in SN1-like transition state; Base-deprotonation of acceptor group in transition-state (Catalytic mechanism)

P 3.1143.50000.64 : Asp/Arg/Gln (Residues/cofactors in Protein)


1st Nucleophile : an acceptor group in substrate
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • S00413 : (reaction 2) 6.3.1.1; Aspartate--ammonia ligase (Catalytic domain; 3.30.930.10)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)