RLCP 3.1177.805.79 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.1177.-.- : Acyl group from Sulfur atom to Sulfur atom (Ligand group involved)

C 3.1177.805.- : Dihydrolipoamide-succinyltransferase-like mechanism (Acid-Base/Modulator/Stabilizer); SN2-like reaction; Modulator-assisted base activation of acceptor group; Nucleophilic attack on transferred group by activated acceptor group; Stablization of transition state & Modulator-assisted acid protonation to transferred group (Catalytic mechanism)

P 3.1177.805.79 : His/Asn + mainchain carbonyl + a residue with hydroxyl group [Ser or Thr] (Residues/cofactors in Protein)

1st Nucleophile : an acceptor group in substrate
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • M00189 :; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (Catalytic domain; 3.30.559.10)