RLCP 3.1197.15025.150 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.1197.-.- : Acyl group from Sulfur atom to Carbon (double-bonded; sp2) (Ligand group involved)

C 3.1197.15025.- : Beta-ketoacyl-ACP synthase II 3rd reaction step-like mechanism (Stabilizer-Acid/Stabilizer); Stabilization of acceptor; Nucleophilic attack of acceptor on transferred group forming an intermediate; Stabilization of intermediate; Acid protonation to leaving group (SN2-like reaction) (Catalytic mechanism)

P 3.1197.15025.150 : His + mainchain amide groups + Cys covalently-bound to substrate/intermediate (Residues/cofactors in Protein)

1st Nucleophile : an acceptor group in substrate
Catalytic groups : groups in residue/substrate
General Base : non-existent
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • D00871 : (reaction 3); 3-oxoacyl-[acyl-carrier-protein] synthase 2 (Catalytic domain;