RLCP 3.133.90030.398 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.133.-.- : Phosphate group from Phosphate oxygen to Phosphate oxygen (Ligand group involved)

C 3.133.90030.- : Thymidylate-kinase-like mechanism (Stabilizer); Inorganic-cofactor-assisted nucleophilic attack by acceptor group on transferred group; SN2-like direct reaction; Transition state stabilized by cofactor and stabilizer; Inorganic-cofactor interacting with transferred/leaving groups (Catalytic mechanism)

P 3.133.90030.398 : Lys/Arg cluster + magnesium ion bound to Ser or Thr (Residues/cofactors in Protein)


1st Nucleophile : an acceptor group in substrate
Catalytic groups : cofactor + groups in residue/substrate
General Base : non-existent
General Acid : non-existent



Related Enzymes

There is one entry in this class.
  • S00306 : 2.7.4.9; Thymidylate kinase (Catalytic domain; 3.40.50.300)