EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 3.-.-.- : Transfer (bond cleavage and new bond formation) (Reaction)

L 3.676.-.- : Peroxide oxygen from peroxide oxygen to sulfur atom (Ligand group involved)

C 3.676.249900.- : 1-Cys-Peroxiredoxin 1st reaction step-like mechanism (Nucleophile/Modulator-Stabilizer/Stabilizer); Modulator-assisted activation of nucleophile; Nucleohile attacks on transferred group; Stabilization of acceptor/transferred/leaving groups; SN2-like reaction (Catalytic mechanism)

P 3.676.249900.37 : Cys + Arg + [Thr or Ser] + mainchain amide groups (Residues/cofactors in Protein)


1st Nucleophile : a catalytic residue
Catalytic groups : groups in residue/substrate
General Base : non-existent
General Acid : non-existent

Related Enzymes

There are 3 entries in this class.
  • D00869 : (reaction 1) 1.11.1.15; Hybrid peroxiredoxin hyPrx5 (Catalytic domain; 3.40.30.10)
  • D00870 : (reaction 1) 1.11.1.15; 1-Cys peroxiredoxin (Catalytic domain; 3.40.30.10)
  • S00916 : (reaction 1) 1.11.1.15; Putative peroxiredoxin Rv2238c/MT2298 (Catalytic domain; 3.40.30.10)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)