RLCP 4.151.766500.451 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 4.-.-.- : Addition to double-bond (new bond formation and decreased bond-order) (Reaction)

L 4.151.-.- : Carbon (sp2) (C=C-O) to Carbonyl carbon (sp2) (Ligand group involved)

C 4.151.766500.- : Modulator-Acid/Stabilizer; Inorganic-cofactor-assisted stabilization of added group of substrate; Modulator-assisted activation of electrophilic unsaturated group; Added group attacks on unsaturated group forming covalent bond; Acid protonation to protonation site of unsaturated group (Catalytic mechanism)

P 4.151.766500.451 : An acidic residue + Asn (or Gln) + zinc ion bound to His cluster (Residues/cofactors in Protein)

1st Nucleophile : Added group (substrate or water)
Catalytic groups : cofactor + groups in residue/substrate
General Base : non-existent
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • S00235 : (reaction 2); Fructose-bisphosphate aldolase class 2 (Catalytic domain;