EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 5.-.-.- : Eliminative double-bond formation (bond cleavage and increased bond-order) (Reaction)

L 5.115.-.- : Methylene (adjacent to double-bonded sp2 carbon ) from Carboxylate (sp2) [release of CO2] (Ligand group involved)

C 5.115.129300.- : Beta-ketoacyl-ACP synthase III 2nd reaction step-like mechanism (Base-Stabilizer/Stabilizer); Stabilization of different site a few bonds away from elimination site in eliminated group; Base deprotonates deprotonation site in leaving group; E1cb-like reaction (Catalytic mechanism)

P 5.115.129300.66 : His + [Asn or Gln] (Residues/cofactors in Protein)


1st Nucleophile : non-existent
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There are 3 entries in this class.
  • D00825 : (reaction 2) 2.3.1.180; 3-oxoacyl-[acyl-carrier-protein] synthase 3 (Catalytic domain; 3.40.47.10)
  • D00826 : (reaction 2) 2.3.1.180; 3-oxoacyl-[acyl-carrier-protein] synthase 3 (Catalytic domain; 3.40.47.10)
  • D00867 : (reaction 2) 2.3.1.180; 3-oxoacyl-[acyl-carrier-protein] synthase 3 (Catalytic domain; 3.40.47.10)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)