EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 5.-.-.- : Eliminative double-bond formation (bond cleavage and increased bond-order) (Reaction)

L 5.115.-.- : Methylene (adjacent to double-bonded sp2 carbon ) from Carboxylate (sp2) [release of CO2] (Ligand group involved)

C 5.115.3380000.- : Stabilizer; Inorganic cofactor-assisted stabilization of eliminated group & Leaving group stabilized; Bond-cleavage occurs by E1-like reaction (Catalytic mechanism)

P 5.115.3380000.410 : Tyr + a divalent metal ion bound to His/Asp/Lys (Residues/cofactors in Protein)


1st Nucleophile : non-existent
Catalytic groups : cofactor + groups in residue/substrate
General Base : non-existent
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • T00084 : (reaction 1) 4.1.1.49; Phosphoenolpyruvate carboxykinase {ATP} (Catalytic domains; 2.170.8.10, 3.40.449.10, 3.90.228.20)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)