RLCP 5.151.2325000.451 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 5.-.-.- : Eliminative double-bond formation (bond cleavage and increased bond-order) (Reaction)

L 5.151.-.- : Carbon (sp2) (C=C-O) from Carbon (sp3) (with hydroxyl group) [leading to carbonyl group] (Ligand group involved)

C 5.151.2325000.- : Modulator-Acid/Stabilizer; Inorganic-cofactor-assisted stabilization of eliminated group; Modulator-assisted activation of eliminated group; Base deprotonation of deprotonation site of leaving group; Bond cleavage of eliminated group and double-bond formation by E2-like reaction (Catalytic mechanism)

P 5.151.2325000.451 : An acidic residue + Asn (or Gln) + zinc ion bound to His cluster (Residues/cofactors in Protein)

1st Nucleophile : non-existent
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • S00235 : (reaction 3); Fructose-bisphosphate aldolase class 2 (Catalytic domain;