RLCP 5.161.586000.968 :EzCatDB EzCatDB

Hierarchic Classification of Catalytic Mechanisms

R 5.-.-.- : Eliminative double-bond formation (bond cleavage and increased bond-order) (Reaction)

L 5.161.-.- : Carbon (sp2) (C=C-N) from Carbon (sp3) (with hydroxyl group) [leading to carbonyl group] (Ligand group involved)

C 5.161.586000.- : Base-Acid-Stabilizer;Acid-Base;Modulator; Modulator-assisted 1st base deprotonation of eliminated group & 1st acid protonation to elimination site of eliminated group leading to transition state; 2nd base deprotonation of deprotonation site leading to bond cleavage & 2nd acid protonation to eliminated group; E2-like reaction (Catalytic mechanism)

P 5.161.586000.968 : Two acidic residues + Thr (Residues/cofactors in Protein)

1st Nucleophile : non-existent
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • T00089 : (reaction 1); Tryptophan synthase alpha chain (Catalytic domains;,