EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 5.-.-.- : Eliminative double-bond formation (bond cleavage and increased bond-order) (Reaction)

L 5.204.-.- : Amine group from Carbon (sp3) adjacent to double-bond (Ligand group involved)

C 5.204.2187010.- : Stabilizer/Electrophile; Initial state is electrophilic anion (no need to deprotonation of deprotonation site); Electrophilic modified residue-assisted bond cleavage; Eliminated group stabilized; E1cb-like reaction; (Catalytic mechanism)

P 5.204.2187010.9090 : Tyr/Asn/Asn + MIO (Ala-Ser-Gly modified residues) (Residues/cofactors in Protein)


1st Nucleophile : non-existent
Catalytic groups : cofactor + groups in residue/substrate
General Base : non-existent
General Acid : non-existent

Related Enzymes

There is one entry in this class.
  • D00267 : (reaction 4) 4.3.1.3; Histidine ammonia-lyase (Catalytic domains; 1.10.275.10, 1.20.200.10)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)