RLCP 6.20.93000.5520 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 6.-.-.- : Exchange of double-bonded atoms (Schiff-base related reaction) (Reaction)

L 6.20.-.- : Schiff-base nitrogen to Carbonyl oxygen (Schiff-base deformation; hydration) (Ligand group involved)

C 6.20.93000.- : Base/Modulator; Base-activated substituted group attacks on double-bond partner atom; Formation of tetrahedral intermediate; Organic-cofactor-assisted deprotonation of 3rd base; 3rd base activation of lone pair on nucleophile; Lone pair on nucleophile attacks again on doulbe-bond partner atom; Organic-cofactor-assisted protonation to leaving group (Catalytic mechanism)

P 6.20.93000.5520 : Lys/Tyr + PLP double-bonded to substrate/intermediate (Residues/cofactors in Protein)


1st Nucleophile : Substituted group (substrate or water)
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : a group in substrate/cofactor

Related Enzymes

There is one entry in this class.
  • D00106 : (reaction 3) 2.6.1.42; Branched-chain-amino-acid aminotransferase (Catalytic domain; 3.20.10.10)