RLCP 6.30.83700.5070 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 6.-.-.- : Exchange of double-bonded atoms (Schiff-base related reaction) (Reaction)

L 6.30.-.- : Exchange of Schiff-base nitrogen atoms (external aldimine formation) (Ligand group involved)

C 6.30.83700.- : Base-Acid-Base; Base-activated substituted group attacks on double-bond partner atom; Acid protonation to leaving group; Formation of tetrahedral intermediate; 2nd base deprotonation of substituted group; Lone pair on nucleophile attacks again on double-bond partner atom; Organic-cofactor-assisted reaction (Catalytic mechanism)

P 6.30.83700.5070 : An acidic residue + PLP double-bonded to Lys (Residues/cofactors in Protein)


1st Nucleophile : Substituted group (substrate or water)
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • T00089 : (reaction 2) 4.2.1.20; Tryptophan synthase alpha chain (Catalytic domains; 3.20.20.70, 3.40.50.1100)