RLCP 8.113.585900.479 :EzCatDB EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms

R 8.-.-.- : Isomerization (shift of double-bond position) (Reaction)

L 8.113.-.- : Adjacent bond; C=C-O to C-C=O (Ligand group involved)

C 8.113.585900.- : Acid-Base/Acid; Inorganic-cofactor-assisted stabilization of initially single-bonded atom and adjacent atom to double-bonded atom; Acid protonation to double-bonded atom & Base deprotonation of single-bonded atom; 2nd Acid protonation to adjacent atom to initially-double-bonded atom (Catalytic mechanism)

P 8.113.585900.479 : Two acidic residues + zinc ion bound to Gln/His/Glu & substrate/intermediate (Residues/cofactors in Protein)


1st Nucleophile : non-existent
Catalytic groups : cofactor + groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There is one entry in this class.
  • S00185 : (reaction 3) 4.4.1.5; Lactoylglutathione lyase (Catalytic domain; 3.10.180.10)