EzCatDB

R L C P
Hierarchic Classification of Catalytic Mechanisms


R 8.-.-.- : Isomerization (shift of double-bond position) (Reaction)

L 8.131.-.- : Adjacent bond; O=C-C to O-C=C (Ligand group involved)

C 8.131.42001.- : Base-Acid/Stabilizers; Base deprotonation of initially single-bonded atom leading to intermediate formation; Intermediate stabilized; Acid protonation to initially double-bonded atom (Catalytic mechanism)

P 8.131.42001.6 : An acidic residue + His/Lys (Residues/cofactors in Protein)


1st Nucleophile : non-existent
Catalytic groups : groups in residue/substrate
General Base : a catalytic residue
General Acid : a catalytic residue

Related Enzymes

There are 2 entries in this class.
  • S00225 : (reaction 1) 5.3.1.1; Triosephosphate isomerase (Catalytic domain; 3.20.20.70)
  • T00239 : (reaction 2) 2.7.2.3, 5.3.1.1; Bifunctional PGK/TIM (Catalytic domains; 3.20.20.70, 3.40.50.1260, 3.40.50.1270)
  • Copyright: Nozomi Nagano, JST & CBRC-AIST
    Funded by PRESTO/Japan Science and Technology Agency (JST) (December 2001 - November 2004)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2006)
    Funded by Grant-in-Aid for Scientific Research (B)/Japan Society for the Promotion of Science (JSPS) (April 2005 - March 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (September 2005 - September 2008)
    Funded by BIRD/Japan Science and Technology Agency (JST) (October 2007 - September 2010)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2011 - March 2012)
    Funded by Grant-in-Aid for Publication of Scientific Research Results/Japan Society for the Promotion of Science (JSPS) (April 2012 - March 2013)
    Supported by the commission for the Development of Artificial Gene Synthesis Technology for Creating Innovative Biomaterial from the Ministry of Economy, Trade and Industry (METI) (October 2012 - March 2016)
    Funded by the project commissioned by the New Energy and Industrial Technology Development Organization (NEDO) (April 2016 -)