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References
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[1]
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Resource
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Comments
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Medline ID
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PubMed ID
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3893537
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Journal
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Biochemistry
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Year
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1985
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Volume
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24
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Pages
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1831-41
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Authors
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Harper JW, Hemmi K, Powers JC
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Title
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Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor.
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Related PDB
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Related UniProtKB
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[2]
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Resource
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Comments
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Medline ID
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PubMed ID
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3910097
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Journal
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Biochemistry
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Year
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1985
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Volume
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24
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Pages
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7200-13
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Authors
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Harper JW, Powers JC
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Title
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Reaction of serine proteases with substituted 3-alkoxy-4-chloroisocoumarins and 3-alkoxy-7-amino-4-chloroisocoumarins: new reactive mechanism-based inhibitors.
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Related PDB
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Related UniProtKB
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[3]
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Resource
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Comments
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Medline ID
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PubMed ID
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1334431
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Journal
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Biochemistry
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Year
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1992
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Volume
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31
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Pages
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12785-91
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Authors
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Sreenivasan U, Axelsen PH
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Title
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Buried water in homologous serine proteases.
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Related PDB
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Related UniProtKB
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[4]
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Resource
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Comments
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Medline ID
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PubMed ID
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7682557
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Journal
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J Biol Chem
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Year
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1993
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Volume
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268
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Pages
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9023-34
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Authors
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Sali A, Matsumoto R, McNeil HP, Karplus M, Stevens RL
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Title
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Three-dimensional models of four mouse mast cell chymases. Identification of proteoglycan binding regions and protease-specific antigenic epitopes.
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Related PDB
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Related UniProtKB
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[5]
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Resource
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Comments
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Medline ID
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PubMed ID
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8226889
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Journal
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J Biol Chem
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Year
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1993
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Volume
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268
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Pages
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23626-33
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Authors
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Schechter NM, Jordan LM, James AM, Cooperman BS, Wang ZM, Rubin H
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Title
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Reaction of human chymase with reactive site variants of alpha 1-antichymotrypsin. Modulation of inhibitor versus substrate properties.
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Related PDB
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Related UniProtKB
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[6]
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Resource
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Comments
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Medline ID
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PubMed ID
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8962677
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Journal
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Biol Chem Hoppe Seyler
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Year
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1995
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Volume
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376
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Pages
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681-4
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Authors
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Wang ZM, Rubin H, Schechter NM
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Title
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Production of active recombinant human chymase from a construct containing the enterokinase cleavage site of trypsinogen in place of the native propeptide sequence.
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Related PDB
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Related UniProtKB
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[7]
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Resource
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Comments
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X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS).
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Medline ID
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98062898
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PubMed ID
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9400368
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Journal
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Biochemistry
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Year
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1997
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Volume
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36
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Pages
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14318-24
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Authors
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McGrath ME, Mirzadegan T, Schmidt BF
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Title
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Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A.
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Related PDB
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1klt
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Related UniProtKB
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P23946
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[8]
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Resource
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Comments
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Medline ID
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PubMed ID
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9006943
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Journal
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J Biol Chem
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Year
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1997
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Volume
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272
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Pages
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2963-8
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Authors
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Sanker S, Chandrasekharan UM, Wilk D, Glynias MJ, Karnik SS, Husain A
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Title
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Distinct multisite synergistic interactions determine substrate specificities of human chymase and rat chymase-1 for angiotensin II formation and degradation.
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Related PDB
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Related UniProtKB
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[9]
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Resource
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Comments
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Medline ID
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PubMed ID
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9305913
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Journal
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J Biol Chem
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Year
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1997
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Volume
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272
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Pages
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24499-507
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Authors
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Schechter NM, Plotnick M, Selwood T, Walter M, Rubin H
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Title
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Diverse effects of pH on the inhibition of human chymase by serpins.
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Related PDB
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Related UniProtKB
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[10]
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Resource
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Comments
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Medline ID
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PubMed ID
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9216834
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Journal
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J Med Chem
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Year
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1997
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Volume
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40
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Pages
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2156-63
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Authors
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Niwata S, Fukami H, Sumida M, Ito A, Kakutani S, Saitoh M, Suzuki K, Imoto M, Shibata H, Imajo S, Kiso Y, Tanaka T, Nakazato H, Ishihara T, Takai S, Yamamoto D, Shiota N, Miyazaki M, Okunishi H, Kinoshita A, Urata H, Arakawa K
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Title
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Substituted 3-(phenylsulfonyl)-1-phenylimidazolidine-2,4-dione derivatives as novel nonpeptide inhibitors of human heart chymase.
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Related PDB
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Related UniProtKB
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[11]
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Resource
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Comments
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Medline ID
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PubMed ID
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10508424
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Journal
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Biochemistry
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Year
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1999
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Volume
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38
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Pages
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12187-95
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Authors
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Pejler G, Sadler JE
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Title
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Mechanism by which heparin proteoglycan modulates mast cell chymase activity.
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Related PDB
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Related UniProtKB
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[12]
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Resource
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Comments
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X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS).
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Medline ID
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99134396
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PubMed ID
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9931257
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Journal
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J Mol Biol
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Year
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1999
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Volume
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286
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Pages
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163-73
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Authors
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Pereira PJ, Wang ZM, Rubin H, Huber R, Bode W, Schechter NM, Strobl S
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Title
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The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity.
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Related PDB
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1pjp
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Related UniProtKB
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P23946
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[13]
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Resource
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Comments
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Medline ID
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PubMed ID
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11209755
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Journal
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Biol Chem
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Year
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2000
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Volume
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381
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Pages
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1203-14
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Authors
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Estebanez-Perpina E, Fuentes-Prior P, Belorgey D, Braun M, Kiefersauer R, Maskos K, Huber R, Rubin H, Bode W
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Title
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Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.
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Related PDB
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Related UniProtKB
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[14]
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Resource
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Comments
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Medline ID
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PubMed ID
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10698435
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Journal
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Bioorg Med Chem Lett
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Year
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2000
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Volume
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10
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Pages
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199-201
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Authors
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Hayashi Y, Iijima K, Katada J, Kiso Y
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Title
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Structure-activity relationship studies of chloromethyl ketone derivatives for selective human chymase inhibitors.
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Related PDB
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Related UniProtKB
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[15]
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Resource
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Comments
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Medline ID
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PubMed ID
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11350059
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Journal
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Biochem Biophys Res Commun
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Year
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2001
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Volume
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283
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Pages
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831-6
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Authors
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Sakaguchi M, Yamamoto D, Takai S, Jin D, Taniguchi M, Baba K, Miyazaki M
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Title
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Inhibitory mechanism of daphnodorins for human chymase.
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Related PDB
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Related UniProtKB
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[16]
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Resource
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Comments
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Medline ID
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PubMed ID
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11747453
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Journal
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Biochemistry
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Year
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2001
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Volume
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40
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Pages
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15762-70
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Authors
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Cooley J, Takayama TK, Shapiro SD, Schechter NM, Remold-O'Donnell E
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Title
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The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites.
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Related PDB
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Related UniProtKB
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[17]
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Resource
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Comments
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Medline ID
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PubMed ID
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12007614
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Journal
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Biochim Biophys Acta
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Year
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2002
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Volume
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1596
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Pages
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346-56
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Authors
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Muilenburg DJ, Raymond WW, Wolters PJ, Caughey GH
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Title
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Lys40 but not Arg143 influences selectivity of angiotensin conversion by human alpha-chymase.
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Related PDB
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Related UniProtKB
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[18]
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Resource
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Comments
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Medline ID
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PubMed ID
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12614156
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Journal
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Biochemistry
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Year
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2003
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Volume
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42
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Pages
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2616-24
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Authors
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Reiling KK, Krucinski J, Miercke LJ, Raymond WW, Caughey GH, Stroud RM
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Title
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Structure of human pro-chymase: a model for the activating transition of granule-associated proteases.
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Related PDB
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Related UniProtKB
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[19]
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Resource
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Comments
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Medline ID
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PubMed ID
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12815038
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Journal
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J Biol Chem
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Year
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2003
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Volume
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278
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Pages
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34517-24
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Authors
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Raymond WW, Ruggles SW, Craik CS, Caughey GH
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Title
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Albumin is a substrate of human chymase. Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site.
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Related PDB
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Related UniProtKB
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