DB code: M00039

CATH domain 3.30.365.10 : Aldehyde Oxidoreductase; domain 4 Catalytic domain
3.30.365.10 : Aldehyde Oxidoreductase; domain 4 Catalytic domain
3.30.43.10 : Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2
3.30.390.50 : Enolase-like; domain 1
3.30.465.10 : Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Catalytic domain
3.10.20.30 : Ubiquitin-like (UB roll) Catalytic domain
1.10.150.120 : DNA polymerase; domain 1 Catalytic domain
3.90.1170.50 : Aldehyde Oxidoreductase; domain 3
3.30.365.10 : Aldehyde Oxidoreductase; domain 4
3.30.365.10 : Aldehyde Oxidoreductase; domain 4
E.C. 1.2.99.2
CSA 1qj2
M-CSA 1qj2
MACiE M0107

CATH domain Related DB codes (homologues)
3.10.20.30 : Ubiquitin-like (UB roll) M00042 M00049
3.30.43.10 : Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 M00001 M00004 M00179 T00003
3.30.465.10 : Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 T00003

Uniprot Enzyme Name
UniprotKB Protein name Synonyms RefSeq Pfam
P19921 Carbon monoxide dehydrogenase small chain
CO dehydrogenase subunit S
CO-DH S
EC 1.2.99.2
YP_004638432.1 (Protein)
NC_015689.1 (DNA/RNA sequence)
PF00111 (Fer2)
PF01799 (Fer2_2)
[Graphical View]
P19919 Carbon monoxide dehydrogenase large chain
CO dehydrogenase subunit L
CO-DH L
EC 1.2.99.2
YP_004638433.1 (Protein)
NC_015689.1 (DNA/RNA sequence)
PF01315 (Ald_Xan_dh_C)
PF02738 (Ald_Xan_dh_C2)
[Graphical View]
P19920 Carbon monoxide dehydrogenase medium chain
CO dehydrogenase subunit M
CO-DH M
EC 1.2.99.2
YP_004638431.1 (Protein)
NC_015689.1 (DNA/RNA sequence)
PF03450 (CO_deh_flav_C)
PF00941 (FAD_binding_5)
[Graphical View]

KEGG enzyme name
carbon-monoxide dehydrogenase (acceptor)
anaerobic carbon monoxide dehydrogenase
carbon monoxide oxygenase
carbon-monoxide dehydrogenase
carbon-monoxide:(acceptor) oxidoreductase

UniprotKB: Accession Number Entry name Activity Subunit Subcellular location Cofactor
P19921 DCMS_OLICA CO + H(2)O + A = CO(2) + AH(2). Dimer of heterotrimers. Each heterotrimer consists of a large, a medium and a small subunit. Binds 2 2Fe-2S clusters.
P19919 DCML_OLICA CO + H(2)O + A = CO(2) + AH(2). Dimer of heterotrimers. Each heterotrimer consists of a large, a medium and a small subunit. Binds 1 Cu(+) ion per subunit. Binds 1 Mo(6+) ion per subunit. Binds 1 molybdopterin cytosine dinucleotide (MCD) per subunit.
P19920 DCMM_OLICA CO + H(2)O + A = CO(2) + AH(2). Dimer of heterotrimers. Each heterotrimer consists of a large, a medium and a small subunit. Binds 1 FAD per subunit.

KEGG Pathways
Map code Pathways E.C.
MAP00680 Methane metabolism
MAP00633 Trinitrotoluene degradation

Compound table
Cofactors Substrates Products Intermediates
KEGG-id L00023 C99999 L00006 C00016 C00237 C00001 C00028 C00011 C00030
E.C.
Compound [2Fe-2S] Dinuclear [Cu-S-Mo(=O)OH] cluster Molybdopterin cytosine dinucleotide FAD CO H2O Acceptor CO2 Reduced acceptor
Type heavy metal,sulfide group heavy metal,sulfide group amide group,amine group,aromatic ring (with nitrogen atoms),carbohydrate,nucleotide ,sulfhydryl group amide group,amine group,aromatic ring (only carbon atom),aromatic ring (with nitrogen atoms),carbohydrate,nucleotide others H2O others others others
ChEBI 33739
43955
16238
17245
15377
16526
PubChem 4369128
643975
281
22247451
962
280
1n5wA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2G01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2G02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:FES Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wE01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60E01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61E01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62E01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63E01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2H01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiE01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wE02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60E02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61E02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62E02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63E02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2H02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiE02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n5wE03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n60B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n60E03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n61B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n61E03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n62B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n62E03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n63B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n63E03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1qj2B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Analogue:PCD Unbound Unbound Unbound Unbound Unbound Unbound
1qj2H03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Analogue:PCD Unbound Unbound Unbound Unbound Unbound Unbound
1zxiB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1zxiE03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Bound:MCN Unbound Unbound Unbound Unbound Unbound Unbound
1n5wB04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:CUM (oxidized) Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wE04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:CUM (oxidized) Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Analogue:OMO Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60E04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Analogue:OMO Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:CUN (reduced) Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61E04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:CUN (reduced) Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Analogue:CUB Unbound Unbound Unbound Unbound Unbound Unbound Intermediate-analogue:CUB
1n62E04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Analogue:CUB Unbound Unbound Unbound Unbound Unbound Unbound Intermediate-analogue:CUB
1n63B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:CUN (reduced) Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63E04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:CUN (reduced) Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2H04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiB04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:CUM (oxidized) Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiE04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:CUM (oxidized) Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wB05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wE05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60E05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61E05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62E05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63E05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2H05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiB05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiE05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wF01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1n60F01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1n61C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1n61F01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1n62C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1n62F01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1n63C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1n63F01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1qj2C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1qj2I01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1zxiC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1zxiF01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Bound:FAD Unbound Unbound Unbound Unbound Unbound
1n5wC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wF02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60F02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61F02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62F02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63F02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2I02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiF02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n5wC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Analogue:FAD Unbound Unbound Unbound Unbound Unbound
1n5wF03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Analogue:FAD Unbound Unbound Unbound Unbound Unbound
1n60C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n60F03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n61F03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n62F03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1n63F03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1qj2I03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound
1zxiF03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound Unbound

Reference for Active-site residues
resource references E.C.
Swiss-prot;P19921, P19919, P19920 & literature [3], [4], [5]

Active-site residues
PDB Catalytic residues Cofactor-binding residues Modified residues Main-chain involved in catalysis Comment
1n5wA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n5wD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n60A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n60D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n61A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n61D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n62A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n62D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n63A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n63D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1qj2A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1qj2G01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1zxiA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1zxiD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 42;CYS 47;CYS 50;CYS 62(2Fe-2S cluster-1 binding)
1n5wA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n5wD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n60A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n60D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n61A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n61D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n62A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n62D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n63A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n63D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1qj2A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1qj2G02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1zxiA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1zxiD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 102;CYS 105;CYS 137;CYS 139(2Fe-2S cluster-2 binding)
1n5wB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wE01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60E01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61E01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62E01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63E01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2H01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiE01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wE02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60E02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61E02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62E02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63E02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2H02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiE02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wE03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60E03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61E03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62E03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63E03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2H03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiE03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wB04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n5wE04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n60B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n60E04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n61B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n61E04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n62B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n62E04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n63B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n63E04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1qj2B04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;GLU 763 EYS 388(Copper binding);GLU 763(Molybdenum binding) EYS 388(Selanylated) ARG 387
1qj2H04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;GLU 763 EYS 388(Copper binding);GLU 763(Molybdenum binding) EYS 388(Selanylated) ARG 387
1zxiB04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1zxiE04 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain CYS 388;GLU 763 CYS 388(Copper binding);GLU 763(Molybdenum binding) ARG 387
1n5wB05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n5wE05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n60B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n60E05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n61B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n61E05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n62B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n62E05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n63B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n63E05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1qj2B05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1qj2H05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1zxiB05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1zxiE05 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain GLN 240
1n5wC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wF01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60F01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61F01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62F01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63F01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2I01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiF01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wF02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60F02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61F02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62F02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63F02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2I02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiF02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n5wF03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n60F03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n61F03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n62F03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1n63F03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qj2I03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1zxiF03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain

References for Catalytic Mechanism
References Sections No. of steps in catalysis
[1]
Fig.4, p.8887-8889
[2]
Fig.5, p.871-875
[3]
Fig.1
[4]
p.1224-1228
[5]
Fig.2, p.15974-15976
[7]
Fig. 2, Fig. 6, Fig. 12, p.891-897

References
[1]
Resource
Comments X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
Medline ID 99362680
PubMed ID 10430865
Journal Proc Natl Acad Sci U S A
Year 1999
Volume 96
Pages 8884-9
Authors Dobbek H, Gremer L, Meyer O, Huber R
Title Crystal structure and mechanism of CO dehydrogenase, a molybdo iron-sulfur flavoprotein containing S-selanylcysteine.
Related PDB 1qj2
Related UniProtKB P19919 P19920 P19921
[2]
Resource
Comments
Medline ID
PubMed ID 11076018
Journal Biol Chem
Year 2000
Volume 381
Pages 865-76
Authors Meyer O, Gremer L, Ferner R, Ferner M, Dobbek H, Gnida M, Meyer-Klaucke W, Huber R
Title The role of Se, Mo and Fe in the structure and function of carbon monoxide dehydrogenase.
Related PDB
Related UniProtKB
[3]
Resource
Comments
Medline ID
PubMed ID 10636886
Journal J Biol Chem
Year 2000
Volume 275
Pages 1864-72
Authors Gremer L, Kellner S, Dobbek H, Huber R, Meyer O
Title Binding of flavin adenine dinucleotide to molybdenum-containing carbon monoxide dehydrogenase from Oligotropha carboxidovorans. Structural and functional analysis of a carbon monoxide dehydrogenase species in which the native flavoprotein has been replaced by its recombinant counterpart produced in Escherichia coli.
Related PDB
Related UniProtKB
[4]
Resource
Comments
Medline ID
PubMed ID 10966817
Journal J Mol Biol
Year 2000
Volume 301
Pages 1221-35
Authors Hanzelmann P, Dobbek H, Gremer L, Huber R, Meyer O
Title The effect of intracellular molybdenum in Hydrogenophaga pseudoflava on the crystallographic structure of the seleno-molybdo-iron-sulfur flavoenzyme carbon monoxide dehydrogenase.
Related PDB
Related UniProtKB
[5]
Resource
Comments X-RAY CRYSTALLOGRAPHY (1.09 ANGSTROMS).
Medline ID 22364130
PubMed ID 12475995
Journal Proc Natl Acad Sci U S A
Year 2002
Volume 99
Pages 15971-6
Authors Dobbek H, Gremer L, Kiefersauer R, Huber R, Meyer O
Title Catalysis at a dinuclear [CuSMo(==O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution.
Related PDB 1n5w 1n60 1n61 1n62 1n63
Related UniProtKB P19919 P19920 P19921
[6]
Resource
Comments
Medline ID
PubMed ID 12515558
Journal Biochemistry
Year 2003
Volume 42
Pages 222-30
Authors Gnida M, Ferner R, Gremer L, Meyer O, Meyer-Klaucke W
Title A novel binuclear [CuSMo] cluster at the active site of carbon monoxide dehydrogenase: characterization by X-ray absorption spectroscopy.
Related PDB
Related UniProtKB
[7]
Resource
Comments
Medline ID
PubMed ID 15834924
Journal J Comput Chem
Year 2005
Volume 26
Pages 888-98
Authors Siegbahn PE, Shestakov AF
Title Quantum chemical modeling of CO oxidation by the active site of molybdenum CO dehydrogenase.
Related PDB
Related UniProtKB
[8]
Resource
Comments
Medline ID
PubMed ID 16091936
Journal J Biol Inorg Chem
Year 2005
Volume 10
Pages 518-28
Authors Resch M, Dobbek H, Meyer O
Title Structural and functional reconstruction in situ of the [CuSMoO2] active site of carbon monoxide dehydrogenase from the carbon monoxide oxidizing eubacterium Oligotropha carboxidovorans.
Related PDB 1zxi
Related UniProtKB

Comments
This enzyme is composed of large subunits with dinuclear cluster of Mo and Cu along with Molybdopterin cytosine dinucleotide(MCD) as cofactors, small subunits with two iron-sulfur clusters, and medium subunits with FAD as cofactor.
Ni-containing carbon monoxide dehydrogenases and bifunctional enzymes (with acetyl-CoA synthetase) are not homologous, which classified into the identical E.C.
According to the literature [3], this enzyme catalyzes the following reactions:
(A) Oxidation of CO with H2O, yielding CO2, two electrons and two protons (H+) ions:
(B) Electron transfer from CO to S-selanylcysteine 388 (EYS 388 of 1qj2):
(C) Electron transfer from S-selanylcysteine 388 (EYS 388 of 1qj2) to Molybdenum cofactor:
(D) Electron transfer from Molybdenum cofactor to MCD cofactor:
(E) Electron transfer from MCD cofactor to 2Fe-2S cluster-2:
(F) Electron transfer from 2Fe-2S cluster-2 to 2Fe-2S cluster-1:
(G) Electron transfer from 2Fe-2S cluster-1 to flavin group of FAD:
(H) Electron transfer from flavin group of FAD to electron acceptor protein:

Created Updated
2005-06-03 2009-02-26