References
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[1]
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Resource
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Comments
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Medline ID
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PubMed ID
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9843392
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Journal
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Biochemistry
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Year
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1998
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Volume
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37
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Pages
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15865-76
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Authors
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Perez-Canadillas JM, Campos-Olivas R, Lacadena J, Martinez del Pozo A, Gavilanes JG, Santoro J, Rico M, Bruix M
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Title
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Characterization of pKa values and titration shifts in the cytotoxic ribonuclease alpha-sarcin by NMR. Relationship between electrostatic interactions, structure, and catalytic function.
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Related PDB
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Related UniProtKB
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[2]
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Resource
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Comments
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X-ray crystallography
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Medline ID
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PubMed ID
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10843858
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Journal
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J Mol Biol
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Year
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2000
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Volume
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299
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Pages
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1061-73
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Authors
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Perez-Canadillas JM, Santoro J, Campos-Olivas R, Lacadena J, Martinez del Pozo A, Gavilanes JG, Rico M, Bruix M
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Title
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The highly refined solution structure of the cytotoxic ribonuclease alpha-sarcin reveals the structural requirements for substrate recognition and ribonucleolytic activity.
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Related PDB
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1de3
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Related UniProtKB
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[3]
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Resource
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Comments
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catalysis
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Medline ID
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PubMed ID
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11025546
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Journal
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Proteins
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Year
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2000
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Volume
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41
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Pages
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350-61
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Authors
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de Antonio C, Martinez del Pozo A, Mancheno JM, Onaderra M, Lacadena J, Martinez-Ruiz A, Perez-Canadillas JM, Bruix M, Gavilanes JG
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Title
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Assignment of the contribution of the tryptophan residues to the spectroscopic and functional properties of the ribotoxin alpha-sarcin.
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Related PDB
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Related UniProtKB
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[4]
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Resource
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Comments
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catalysis
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Medline ID
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PubMed ID
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11313342
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Journal
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J Biol Chem
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Year
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2001
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Volume
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276
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Pages
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24075-81
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Authors
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Rajamohan F, Mao C, Uckun FM
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Title
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Binding interactions between the active center cleft of recombinant pokeweed antiviral protein and the alpha-sarcin/ricin stem loop of ribosomal RNA.
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Related PDB
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Related UniProtKB
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[5]
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Resource
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Comments
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Medline ID
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PubMed ID
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12527386
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Journal
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FEBS Lett
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Year
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2003
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Volume
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534
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Pages
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197-201
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Authors
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Perez-Canadilllas JM, Garcia-Mayoral MF, Laurents DV, Martinez del Pozo A, Gavilanes JG, Rico M, Bruix M
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Title
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Tautomeric state of alpha-sarcin histidines. Ndelta tautomers are a common feature in the active site of extracellular microbial ribonucleases.
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Related PDB
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Related UniProtKB
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[6]
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Resource
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Comments
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Medline ID
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PubMed ID
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14609322
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Journal
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Biochemistry
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Year
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2003
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Volume
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42
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Pages
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13122-33
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Authors
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Garcia-Mayoral MF, Perez-Canadillas JM, Santoro J, Ibarra-Molero B, Sanchez-Ruiz JM, Lacadena J, Martinez del Pozo A, Gavilanes JG, Rico M, Bruix M
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Title
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Dissecting structural and electrostatic interactions of charged groups in alpha-sarcin. An NMR study of some mutants involving the catalytic residues.
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Related PDB
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Related UniProtKB
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[7]
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Resource
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Comments
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Medline ID
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PubMed ID
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15044731
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Journal
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Protein Sci
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Year
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2004
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Volume
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13
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Pages
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1000-11
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Authors
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Garcia-Mayoral MF, Garcia-Ortega L, Lillo MP, Santoro J, Martinez del Pozo A, Gavilanes JG, Rico M, Bruix M
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Title
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NMR structure of the noncytotoxic alpha-sarcin mutant Delta(7-22): the importance of the native conformation of peripheral loops for activity.
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Related PDB
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1r4y
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Related UniProtKB
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