DB code: S00382

CATH domain 3.40.50.9100 : Rossmann fold Catalytic domain
E.C. 4.2.1.10
CSA
M-CSA
MACiE M0055

CATH domain Related DB codes (homologues)

Uniprot Enzyme Name
UniprotKB Protein name Synonyms RefSeq Pfam
P15474 3-dehydroquinate dehydratase
3-dehydroquinase
EC 4.2.1.10
Type II DHQase
NP_626225.1 (Protein)
NC_003888.3 (DNA/RNA sequence)
PF01220 (DHquinase_II)
[Graphical View]
P0A4Z6 3-dehydroquinate dehydratase
3-dehydroquinase
EC 4.2.1.10
Type II DHQase
NP_217053.1 (Protein)
NC_000962.3 (DNA/RNA sequence)
NP_337108.1 (Protein)
NC_002755.2 (DNA/RNA sequence)
YP_006515978.1 (Protein)
NC_018143.1 (DNA/RNA sequence)
PF01220 (DHquinase_II)
[Graphical View]
P54517 3-dehydroquinate dehydratase
3-dehydroquinase
EC 4.2.1.10
Type II DHQase
NP_390327.1 (Protein)
NC_000964.3 (DNA/RNA sequence)
PF01220 (DHquinase_II)
[Graphical View]

KEGG enzyme name
3-dehydroquinate dehydratase
3-dehydroquinate hydrolase
DHQase
dehydroquinate dehydratase
3-dehydroquinase
5-dehydroquinase
dehydroquinase
5-dehydroquinate dehydratase
5-dehydroquinate hydro-lyase
3-dehydroquinate hydro-lyase

UniprotKB: Accession Number Entry name Activity Subunit Subcellular location Cofactor
P15474 AROQ_STRCO 3-dehydroquinate = 3-dehydroshikimate + H(2)O. Homododecamer.
P0A4Z6 AROQ_MYCTU 3-dehydroquinate = 3-dehydroshikimate + H(2)O. Homododecamer.
P54517 AROQ_BACSU 3-dehydroquinate = 3-dehydroshikimate + H(2)O. Homododecamer.

KEGG Pathways
Map code Pathways E.C.
MAP00400 Phenylalanine, tyrosine and tryptophan biosynthesis

Compound table
Substrates Products Intermediates
KEGG-id C00944 C02637 C00001
E.C.
Compound 3-Dehydroquinate 3-Dehydroshikimate H2O
Type carbohydrate,carboxyl group carbohydrate,carboxyl group H2O
ChEBI 17947
30918
15377
PubChem 439351
439774
22247451
962
1d0iA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iB Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iC Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iD Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iE Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iF Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iG Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iH Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iI Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iJ Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iK Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1d0iL Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0A Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0B Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0C Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0D Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0E Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0F Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0G Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0H Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0I Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0J Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0K Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu0L Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gu1A Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1B Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1C Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1D Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1E Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1F Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1G Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1H Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1I Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1J Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1K Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gu1L Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1gtzA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzB Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzC Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzD Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzE Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzF Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzG Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzH Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzI Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzJ Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzK Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1gtzL Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:DHK
1h05A Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1h0rA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA1 Unbound
1h0sA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:FA6 Unbound
2dhqA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoB Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoC Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoD Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoE Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoF Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoG Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoH Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoI Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoJ Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoK Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoL Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoM Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoN Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoO Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoP Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoQ Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoR Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoS Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoT Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoU Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoV Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoX Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound
1gqoY Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound

Reference for Active-site residues
resource references E.C.
literature [4] & [12]

Active-site residues
PDB Catalytic residues Cofactor-binding residues Modified residues Main-chain involved in catalysis Comment
1d0iA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iB Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iC Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iD Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iE Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iF Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iG Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iH Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iI Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iJ Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iK Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1d0iL Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0A Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0B Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0C Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0D Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0E Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0F Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0G Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0H Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0I Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0J Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0K Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu0L Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1A Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1B Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1C Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1D Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1E Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1F Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1G Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1H Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1I Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1J Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1K Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gu1L Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16;ARG 23;TYR 28;HIS 106
1gtzA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzB Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzC Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzD Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzE Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzF Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzG Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzH Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzI Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzJ Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzK Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1gtzL Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 16; ;TYR 28;HIS 106 mutant R23A
1h05A Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 12;ARG 19; ;HIS 101 invisible 24Y
1h0rA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 12; ;TYR 24;HIS 101 invisible 19R
1h0sA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 12;ARG 19; ;HIS 101 invisible 24Y
2dhqA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 12;ARG 19; ;HIS 101 invisible 24Y
1gqoA Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoB Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoC Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoD Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoE Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoF Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoG Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoH Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoI Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoJ Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoK Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoL Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoM Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoN Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10; ; ;HIS 99 invisible 16-24
1gqoO Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoP Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoQ Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoR Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoS Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoT Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoU Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99
1gqoV Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99 invisible 18-23
1gqoX Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10; ; ;HIS 99 invisible 17-23
1gqoY Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ASN 10;ARG 17; ;HIS 99

References for Catalytic Mechanism
References Sections No. of steps in catalysis
[8]
Fig. 1, p.522 3
[12]
Fig.8, p.497-498 2

References
[1]
Resource
Comments
Medline ID
PubMed ID 1554351
Journal Biochem J
Year 1992
Volume 282
Pages 687-95
Authors Kleanthous C, Deka R, Davis K, Kelly SM, Cooper A, Harding SE, Price NC, Hawkins AR, Coggins JR
Title A comparison of the enzymological and biophysical properties of two distinct classes of dehydroquinase enzymes.
Related PDB
Related UniProtKB
[2]
Resource
Comments
Medline ID
PubMed ID 8064862
Journal J Mol Biol
Year 1994
Volume 241
Pages 488-91
Authors Gourley DG, Coggins JR, Isaacs NW, Moore JD, Charles IG, Hawkins AR
Title Crystallization of a type II dehydroquinase from Mycobacterium tuberculosis.
Related PDB
Related UniProtKB
[3]
Resource
Comments
Medline ID
PubMed ID 8870678
Journal Biochem J
Year 1996
Volume 319
Pages 269-78
Authors Bottomley JR, Hawkins AR, Kleanthous C
Title Conformational changes and the role of metals in the mechanism of type II dehydroquinase from Aspergillus nidulans.
Related PDB
Related UniProtKB
[4]
Resource
Comments
Medline ID
PubMed ID 8798709
Journal J Biol Chem
Year 1996
Volume 271
Pages 24492-7
Authors Krell T, Horsburgh MJ, Cooper A, Kelly SM, Coggins JR
Title Localization of the active site of type II dehydroquinases. Identification of a common arginine-containing motif in the two classes of dehydroquinases.
Related PDB
Related UniProtKB
[5]
Resource
Comments
Medline ID
PubMed ID 9147947
Journal Biochem Soc Trans
Year 1997
Volume 25
Pages 348; replaces 93S
Authors Boam DJ, Price NC, Kelly SM, Krell T, Coggins JR
Title Evidence that the active site in type II dehydroquinase from Streptomyces coelicolor is near the single tryptophan.
Related PDB
Related UniProtKB
[6]
Resource
Comments
Medline ID
PubMed ID 9473305
Journal Arch Biochem Biophys
Year 1998
Volume 350
Pages 298-306
Authors Florova G, Denoya CD, Morgenstern MR, Skinner DD, Reynolds KA
Title Cloning, expression, and characterization of a type II 3-dehydroquinate dehydratase gene from Streptomyces hygroscopicus.
Related PDB
Related UniProtKB
[7]
Resource
Comments
Medline ID
PubMed ID 9931316
Journal Biochem J
Year 1999
Volume 338
Pages 195-202
Authors Price NC, Boam DJ, Kelly SM, Duncan D, Krell T, Gourley DG, Coggins JR, Virden R, Hawkins AR
Title The folding and assembly of the dodecameric type II dehydroquinases.
Related PDB
Related UniProtKB
[8]
Resource
Comments
Medline ID
PubMed ID 10360352
Journal Nat Struct Biol
Year 1999
Volume 6
Pages 521-5
Authors Gourley DG, Shrive AK, Polikarpov I, Krell T, Coggins JR, Hawkins AR, Isaacs NW, Sawyer L
Title The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.
Related PDB 2dhq
Related UniProtKB
[9]
Resource
Comments
Medline ID
PubMed ID 10698442
Journal Bioorg Med Chem Lett
Year 2000
Volume 10
Pages 231-4
Authors Parker EJ, Gonzalez Bello C, Coggins JR, Hawkins AR, Abell C
Title Mechanistic studies on type I and type II dehydroquinase with (6R)- and (6S)-6-fluoro-3-dehydroquinic acids.
Related PDB
Related UniProtKB
[10]
Resource
Comments
Medline ID
PubMed ID 11173479
Journal Acta Crystallogr D Biol Crystallogr
Year 2001
Volume 57
Pages 279-80
Authors Kwak JE, Lee JY, Han BW, Moon J J, Sohn SH, Suh SW
Title Crystallization and preliminary X-ray crystallographic analysis of type II dehydroquinase from Helicobacter pylori.
Related PDB
Related UniProtKB
[11]
Resource
Comments
Medline ID
PubMed ID 12387860
Journal FEBS Lett
Year 2002
Volume 530
Pages 24-30
Authors Evans LD, Roszak AW, Noble LJ, Robinson DA, Chalk PA, Matthews JL, Coggins JR, Price NC, Lapthorn AJ
Title Specificity of substrate recognition by type II dehydroquinases as revealed by binding of polyanions.
Related PDB 1h05
Related UniProtKB
[12]
Resource
Comments X-ray crystallography
Medline ID
PubMed ID 11937054
Journal Structure (Camb)
Year 2002
Volume 10
Pages 493-503
Authors Roszak AW, Robinson DA, Krell T, Hunter IS, Fredrickson M, Abell C, Coggins JR, Lapthorn AJ
Title The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
Related PDB 1d0i 1gu0 1gu1 1gtz
Related UniProtKB
[13]
Resource
Comments
Medline ID
PubMed ID 12784220
Journal Proteins
Year 2003
Volume 51
Pages 616-7
Authors Lee BI, Kwak JE, Suh SW
Title Crystal structure of the type II 3-dehydroquinase from Helicobacter pylori.
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Related UniProtKB

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Created Updated
2004-04-10 2009-02-26