References
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[1]
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Resource
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Comments
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Medline ID
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PubMed ID
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8357796
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Journal
|
Biochemistry
|
Year
|
1993
|
Volume
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32
|
Pages
|
8465-78
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Authors
|
Kim H, Lipscomb WN
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Title
|
X-ray crystallographic determination of the structure of bovine lens leucine aminopeptidase complexed with amastatin: formulation of a catalytic mechanism featuring a gem-diolate transition state.
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Related PDB
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Related UniProtKB
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[2]
|
Resource
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|
Comments
|
X-ray crystallography (1.8 Angstroms)
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Medline ID
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94373500
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PubMed ID
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8087555
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Journal
|
Structure
|
Year
|
1994
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Volume
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2
|
Pages
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283-91
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Authors
|
Chevrier B, Schalk C, D'Orchymont H, Rondeau JM, Moras D, Tarnus C
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Title
|
Crystal structure of Aeromonas proteolytica aminopeptidase: a prototypical member of the co-catalytic zinc enzyme family.
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Related PDB
|
1amp
|
Related UniProtKB
|
Q01693
|
[3]
|
Resource
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Comments
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Medline ID
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|
PubMed ID
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7578088
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Journal
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Biochemistry
|
Year
|
1995
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Volume
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34
|
Pages
|
14792-800
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Authors
|
Strater N, Lipscomb WN
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Title
|
Two-metal ion mechanism of bovine lens leucine aminopeptidase: active site solvent structure and binding mode of L-leucinal, a gem-diolate transition state analogue, by X-ray crystallography.
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Related PDB
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Related UniProtKB
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[4]
|
Resource
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|
Comments
|
X-ray crystallography complex with inhibitor
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Medline ID
|
96215434
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PubMed ID
|
8647077
|
Journal
|
Eur J Biochem
|
Year
|
1996
|
Volume
|
237
|
Pages
|
393-8
|
Authors
|
Chevrier B, D'Orchymont H, Schalk C, Tarnus C, Moras D
|
Title
|
The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit.
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Related PDB
|
1igb
|
Related UniProtKB
|
Q01693
|
[5]
|
Resource
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Comments
|
mechanistic studies, catalysis
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Medline ID
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|
PubMed ID
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9100023
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Journal
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Biochemistry
|
Year
|
1997
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Volume
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36
|
Pages
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4278-86
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Authors
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Chen G, Edwards T, D'souza VM, Holz RC
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Title
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Mechanistic studies on the aminopeptidase from Aeromonas proteolytica: a two-metal ion mechanism for peptide hydrolysis.
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Related PDB
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Related UniProtKB
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[6]
|
Resource
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|
Comments
|
X-ray crystallography (1.9 Angstroms)
|
Medline ID
|
|
PubMed ID
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10413478
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Journal
|
Biochemistry
|
Year
|
1999
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Volume
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38
|
Pages
|
9048-53
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Authors
|
De Paola CC, Bennett B, Holz RC, Ringe D, Petsko GA
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Title
|
1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development.
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Related PDB
|
1cp6
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Related UniProtKB
|
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[7]
|
Resource
|
|
Comments
|
inhibition, catalysis
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Medline ID
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|
PubMed ID
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10471294
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Journal
|
Biochemistry
|
Year
|
1999
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Volume
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38
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Pages
|
11433-9
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Authors
|
Ustynyuk L, Bennett B, Edwards T, Holz RC
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Title
|
Inhibition of the aminopeptidase from Aeromonas proteolytica by aliphatic alcohols. Characterization of the hydrophobic substrate recognition site.
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Related PDB
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Related UniProtKB
|
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[8]
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Resource
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Comments
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Medline ID
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PubMed ID
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10500145
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Journal
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Proc Natl Acad Sci U S A
|
Year
|
1999
|
Volume
|
96
|
Pages
|
11151-5
|
Authors
|
Strater N, Sun L, Kantrowitz ER, Lipscomb WN
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Title
|
A bicarbonate ion as a general base in the mechanism of peptide hydrolysis by dizinc leucine aminopeptidase.
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Related PDB
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Related UniProtKB
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[9]
|
Resource
|
|
Comments
|
inhibition
|
Medline ID
|
|
PubMed ID
|
10569943
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Journal
|
Biochemistry
|
Year
|
1999
|
Volume
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38
|
Pages
|
15587-96
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Authors
|
Huntington KM, Bienvenue DL, Wei Y, Bennett B, Holz RC, Pei D
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Title
|
Slow-binding inhibition of the aminopeptidase from Aeromonas proteolytica by peptide thiols: synthesis and spectroscopic characterization.
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Related PDB
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Related UniProtKB
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[10]
|
Resource
|
|
Comments
|
X-ray crystallography (2.1 Angstroms)
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Medline ID
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|
PubMed ID
|
11401547
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Journal
|
Biochemistry
|
Year
|
2001
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Volume
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40
|
Pages
|
7035-46
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Authors
|
Stamper C, Bennett B, Edwards T, Holz RC, Ringe D, Petsko G
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Title
|
Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis.
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Related PDB
|
1ft7
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Related UniProtKB
|
|
[11]
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Resource
|
|
Comments
|
X-ray crystallography (1.53-1.80 Angstroms)
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Medline ID
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|
PubMed ID
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11484227
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Journal
|
Proteins
|
Year
|
2001
|
Volume
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44
|
Pages
|
490-504
|
Authors
|
Gilboa R, Spungin-Bialik A, Wohlfahrt G, Schomburg D, Blumberg S, Shoham G
|
Title
|
Interactions of Streptomyces griseus aminopeptidase with amino acid reaction products and their implications toward a catalytic mechanism.
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Related PDB
|
|
Related UniProtKB
|
|
[12]
|
Resource
|
|
Comments
|
|
Medline ID
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|
PubMed ID
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11743734
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Journal
|
J Mol Biol
|
Year
|
2001
|
Volume
|
314
|
Pages
|
1191-207
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Authors
|
Wouters MA, Husain A
|
Title
|
Changes in zinc ligation promote remodeling of the active site in the zinc hydrolase superfamily.
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Related PDB
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Related UniProtKB
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