References
|
[1]
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Resource
|
|
Comments
|
X-ray crystallography (2.4 Angstroms)
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Medline ID
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91224078
|
PubMed ID
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2026135
|
Journal
|
EMBO J
|
Year
|
1991
|
Volume
|
10
|
Pages
|
1297-1302
|
Authors
|
Franken S.M., Rozeboom H.J., Kalk K.H., Dijkstra B.W
|
Title
|
Crystal structure of haloalkane dehalogenase: an enzyme to detoxify halogenated alkanes.
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Related PDB
|
2had
|
Related UniProtKB
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[2]
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Resource
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Comments
|
X-ray crystallography, catalysis
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Medline ID
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|
PubMed ID
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8369276
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Journal
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Biochemistry
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Year
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1993
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Volume
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32
|
Pages
|
9031-7
|
Authors
|
Verschueren KH, Kingma J, Rozeboom HJ, Kalk KH, Janssen DB, Dijkstra BW
|
Title
|
Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site.
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Related PDB
|
1edb
1edd
2eda
2edc
|
Related UniProtKB
|
|
[3]
|
Resource
|
|
Comments
|
X-ray crystallography (1.9 Angstroms)
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Medline ID
|
|
PubMed ID
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8355275
|
Journal
|
J Mol Biol
|
Year
|
1993
|
Volume
|
232
|
Pages
|
856-72
|
Authors
|
Verschueren KH, Franken SM, Rozeboom HJ, Kalk KH, Dijkstra BW
|
Title
|
Refined X-ray structures of haloalkane dehalogenase at pH 6.2 and pH 8.2 and implications for the reaction mechanism.
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Related PDB
|
1ede
|
Related UniProtKB
|
|
[4]
|
Resource
|
|
Comments
|
X-ray crystallography (2.4 Angstroms)
|
Medline ID
|
93295480
|
PubMed ID
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8515812
|
Journal
|
Nature
|
Year
|
1993
|
Volume
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363
|
Pages
|
693-8
|
Authors
|
Verschueren K.H.G., Seljee F., Rozeboom H.J., Kalk K.H., Dijkstra B.W
|
Title
|
Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase.
|
Related PDB
|
2dhc
2dhd
2dhe
|
Related UniProtKB
|
|
[5]
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Resource
|
|
Comments
|
catalysis, X-ray crystallography
|
Medline ID
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|
PubMed ID
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8855957
|
Journal
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Biochemistry
|
Year
|
1996
|
Volume
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35
|
Pages
|
13186-95
|
Authors
|
Schanstra JP, Ridder IS, Heimeriks GJ, Rink R, Poelarends GJ, Kalk KH, Dijkstra BW, Janssen DB
|
Title
|
Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate range.
|
Related PDB
|
1hde
|
Related UniProtKB
|
|
[6]
|
Resource
|
|
Comments
|
X-ray crystallography (1.96 Angstroms)
|
Medline ID
|
99007117
|
PubMed ID
|
9790663
|
Journal
|
Biochemistry
|
Year
|
1998
|
Volume
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37
|
Pages
|
15013-23
|
Authors
|
Krooshof G.H., Ridder I.S., Tepper A.W.J.W., Vos G.J., Rozeboom H.J., Kalk K.H., Dijkstra B.W., Janssen D.B
|
Title
|
Kinetic analysis and X-ray structure of haloalkane dehalogenase with a modified halide-binding site.
|
Related PDB
|
1bee
1bez
|
Related UniProtKB
|
|
[7]
|
Resource
|
|
Comments
|
X-ray crystallography (1.15 Angstroms)
|
Medline ID
|
|
PubMed ID
|
10393294
|
Journal
|
Acta Crystallogr D Biol Crystallogr
|
Year
|
1999
|
Volume
|
55
|
Pages
|
1273-90
|
Authors
|
Ridder IS, Rozeboom HJ, Dijkstra BW
|
Title
|
Haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 refined at 1.15 A resolution
|
Related PDB
|
1b6g
|
Related UniProtKB
|
|
[8]
|
Resource
|
|
Comments
|
X-ray crystallography (2.3 Angstroms)
|
Medline ID
|
99438358
|
PubMed ID
|
10508409
|
Journal
|
Biochemistry
|
Year
|
1999
|
Volume
|
38
|
Pages
|
12052-61
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Authors
|
Pikkemaat M.G., Ridder I.S., Rozeboom H.J., Kalk K.H., Dijkstra B.W., Janssen D.B
|
Title
|
Crystallographic and kinetic evidence of a collision complex formed during halide import in haloalkane dehalogenase.
|
Related PDB
|
1cijA
|
Related UniProtKB
|
|
[9]
|
Resource
|
|
Comments
|
X-ray crystallography (1.5 Angstroms)
|
Medline ID
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|
PubMed ID
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10587433
|
Journal
|
Biochemistry
|
Year
|
1999
|
Volume
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38
|
Pages
|
16105-14
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Authors
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Newman J, Peat TS, Richard R, Kan L, Swanson PE, Affholter JA, Holmes IH, Schindler JF, Unkefer CJ, Terwilliger TC
|
Title
|
Haloalkane dehalogenases: structure of a Rhodococcus enzyme.
|
Related PDB
|
1bn6
1bn7
1cqw
|
Related UniProtKB
|
|
[10]
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Resource
|
|
Comments
|
reaction mechanism and substrate specificity (comparative study)
|
Medline ID
|
|
PubMed ID
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10585505
|
Journal
|
Protein Eng
|
Year
|
1999
|
Volume
|
12
|
Pages
|
989-98
|
Authors
|
Damborsky J, Koca J
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Title
|
Analysis of the reaction mechanism and substrate specificity of haloalkane dehalogenases by sequential and structural comparisons.
|
Related PDB
|
|
Related UniProtKB
|
|
[11]
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Resource
|
|
Comments
|
X-ray crystallography (1.58 Angstroms)
|
Medline ID
|
|
PubMed ID
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11087355
|
Journal
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Biochemistry
|
Year
|
2000
|
Volume
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39
|
Pages
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14082-6
|
Authors
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Marek J, Vevodova J, Smatanova IK, Nagata Y, Svensson LA, Newman J, Takagi M, Damborsky J
|
Title
|
Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26.
|
Related PDB
|
1cv2
1d07
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Related UniProtKB
|
|
[12]
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Resource
|
|
Comments
|
catalysis (mutatition analysis)
|
Medline ID
|
|
PubMed ID
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10850790
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Journal
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J Chem Inf Comput Sci
|
Year
|
2000
|
Volume
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40
|
Pages
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839-46
|
Authors
|
Robert D, Girones X, Carbo-Dorca R
|
Title
|
Quantification of the influence of single-point mutations on haloalkane dehalogenase activity: a molecular quantum similarity study.
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Related PDB
|
|
Related UniProtKB
|
|
[13]
|
Resource
|
|
Comments
|
catalysis
|
Medline ID
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|
PubMed ID
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10963662
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Journal
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Proc Natl Acad Sci U S A
|
Year
|
2000
|
Volume
|
97
|
Pages
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9937-42
|
Authors
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Lau EY, Kahn K, Bash PA, Bruice TC
|
Title
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The importance of reactant positioning in enzyme catalysis: a hybrid quantum mechanics/molecular mechanics study of a haloalkane dehalogenase.
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Related PDB
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|
Related UniProtKB
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|
[14]
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Resource
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|
Comments
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catalysis (Erratum in:Biochemistry 2001 Sep 18;40(37):11288)
|
Medline ID
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|
PubMed ID
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11467952
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Journal
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Biochemistry
|
Year
|
2001
|
Volume
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40
|
Pages
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8905-17
|
Authors
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Kmunicek J, Luengo S, Gago F, Ortiz AR, Wade RC, Damborsky J
|
Title
|
Comparative binding energy analysis of the substrate specificity of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10.
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Related PDB
|
|
Related UniProtKB
|
|
[15]
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Resource
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|
Comments
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multiple computer-automated structure evaluation
|
Medline ID
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|
PubMed ID
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11764149
|
Journal
|
Environ Toxicol Chem
|
Year
|
2001
|
Volume
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20
|
Pages
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2681-9
|
Authors
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Damborsky J, Rorije E, Jesenska A, Nagata Y, Klopman G, Peijnenburg WJ
|
Title
|
Structure-specificity relationships for haloalkane dehalogenases.
|
Related PDB
|
|
Related UniProtKB
|
|
[16]
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Resource
|
|
Comments
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|
Medline ID
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|
PubMed ID
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11939779
|
Journal
|
Biochemistry
|
Year
|
2002
|
Volume
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41
|
Pages
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4847-55
|
Authors
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Oakley AJ, Prokop Z, Bohac M, Kmunicek J, Jedlicka T, Monincova M, Kuta-Smatanova I, Nagata Y, Damborsky J, Wilce MC
|
Title
|
Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition.
|
Related PDB
|
1g42
1g4h
1g5f
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Related UniProtKB
|
|
[17]
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Resource
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|
Comments
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|
Medline ID
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|
PubMed ID
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12939138
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Journal
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Biochemistry
|
Year
|
2003
|
Volume
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42
|
Pages
|
10104-12
|
Authors
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Streltsov VA, Prokop Z, Damborsky J, Nagata Y, Oakley A, Wilce MC
|
Title
|
Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates.
|
Related PDB
|
1iz7
1iz8
1k5p
1k63
1k6e
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Related UniProtKB
|
|
[18]
|
Resource
|
|
Comments
|
|
Medline ID
|
|
PubMed ID
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14744129
|
Journal
|
Biochemistry
|
Year
|
2004
|
Volume
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43
|
Pages
|
870-8
|
Authors
|
Oakley AJ, Klvana M, Otyepka M, Nagata Y, Wilce MC, Damborsky J
|
Title
|
Crystal structure of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26 at 0.95 A resolution: dynamics of catalytic residues.
|
Related PDB
|
1mj5
|
Related UniProtKB
|
|