DB code: T00021

CATH domain 2.40.180.10 : Catalase HpII, Chain A, domain 1 Catalytic domain
1.10.422.10 :
3.40.50.880 : Rossmann fold
E.C. 1.11.1.6
CSA 1iph
M-CSA 1iph
MACiE

CATH domain Related DB codes (homologues)
3.40.50.880 : Rossmann fold D00526 M00215 T00114

Uniprot Enzyme Name
UniprotKB Protein name Synonyms RefSeq Pfam
P21179 Catalase HPII
EC 1.11.1.6
Hydroxyperoxidase II
YP_025308.1 (Protein)
NC_000913.2 (DNA/RNA sequence)
YP_489993.1 (Protein)
NC_007779.1 (DNA/RNA sequence)
PF00199 (Catalase)
PF06628 (Catalase-rel)
[Graphical View]

KEGG enzyme name
catalase
equilase
caperase
optidase
catalase-peroxidase
CAT

UniprotKB: Accession Number Entry name Activity Subunit Subcellular location Cofactor
P21179 CATE_ECOLI 2 H(2)O(2) = O(2) + 2 H(2)O. Homotetramer. Cytoplasm (Probable). Heme group.

KEGG Pathways
Map code Pathways E.C.
MAP00680 Methane metabolism
MAP00380 Tryptophan metabolism

Compound table
Cofactors Substrates Products Intermediates
KEGG-id C00032 C00027 C00007 C00001
E.C. (oxoferryl heme, Por+-FeIV=O)
Compound Heme H2O2 O2 H2O Compound I Covalent-bonded Tyr415-His392 Heme hydroxychlorin spirolactone + covalent-bonded Tyr415-His392
Type aromatic ring (with nitrogen atoms),carboxyl group,heavy metal others others H2O
ChEBI 17627
26355
16240
15379
26689
27140
15377
PubChem 22326046
784
977
22247451
962
1cf9A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1cf9B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1cf9C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1cf9D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1gg9A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1gg9B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1gg9C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1gg9D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1ggeA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1ggeB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1ggeC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1ggeD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1ggfA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Bound:2xPEO Unbound Unbound Unbound
1ggfB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Bound:2xPEO Unbound Unbound Unbound
1ggfC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Bound:2xPEO Unbound Unbound Unbound
1ggfD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Bound:2xPEO Unbound Unbound Unbound
1gghA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1gghB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1gghC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1gghD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1ggjA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1ggjB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1ggjC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1ggjD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1ggkA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Intermediate-bound:TYR_415-HIS_392 Unbound
1ggkB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Intermediate-bound:TYR_415-HIS_392 Unbound
1ggkC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Intermediate-bound:TYR_415-HIS_392 Unbound
1ggkD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Intermediate-bound:TYR_415-HIS_392 Unbound
1iphA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1iphB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1iphC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1iphD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p7yA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p7yB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p7yC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p7yD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p7zA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p7zB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p7zC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p7zD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p80A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p80B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p80C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p80D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1p81A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1p81B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1p81C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1p81D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Analogue:HDD Unbound Unbound Unbound Intermediate-bound:HDD-TYR_415-HIS_392
1qf7A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1qf7B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1qf7C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1qf7D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Unbound Unbound
1qwsA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Intermediate-bound:TYR_415-HIS_392 Unbound
1qwsB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Intermediate-bound:TYR_415-HIS_392 Unbound
1qwsC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Intermediate-bound:TYR_415-HIS_392 Unbound
1qwsD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Bound:HEM Unbound Unbound Intermediate-bound:TYR_415-HIS_392 Unbound
1cf9A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1cf9B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1cf9C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1cf9D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gg9A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gg9B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gg9C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gg9D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggeA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggeB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggeC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggeD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggfA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:PEO Unbound Unbound Unbound
1ggfB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:PEO Unbound Unbound Unbound
1ggfC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:PEO Unbound Unbound Unbound
1ggfD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Bound:PEO Unbound Unbound Unbound
1gghA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gghB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gghC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gghD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggjA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggjB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggjC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggjD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggkA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggkB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggkC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggkD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1iphA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1iphB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1iphC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1iphD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7yA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7yB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7yC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7yD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7zA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7zB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7zC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7zD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p80A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p80B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p80C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p80D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p81A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p81B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p81C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p81D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qf7A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qf7B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qf7C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qf7D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qwsA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qwsB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qwsC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qwsD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1cf9A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1cf9B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1cf9C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1cf9D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gg9A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gg9B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gg9C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gg9D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggeA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggeB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggeC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggeD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggfA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggfB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggfC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggfD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gghA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gghB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gghC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1gghD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggjA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggjB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggjC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggjD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggkA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggkB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggkC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1ggkD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1iphA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1iphB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1iphC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1iphD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7yA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7yB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7yC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7yD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7zA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7zB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7zC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p7zD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p80A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p80B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p80C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p80D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p81A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p81B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p81C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1p81D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qf7A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qf7B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qf7C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qf7D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qwsA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qwsB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qwsC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound
1qwsD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain Unbound Unbound Unbound Unbound Unbound

Reference for Active-site residues
resource references E.C.
Swiss-prot;P21179 & literature [4], [5], [7], [9], [11], [13], [16]

Active-site residues
PDB Catalytic residues Cofactor-binding residues Modified residues Main-chain involved in catalysis Comment
1cf9A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant V169C
1cf9B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant V169C
1cf9C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant V169C
1cf9D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant V169C
1gg9A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128N
1gg9B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128N
1gg9C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128N
1gg9D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128N
1ggeA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding)
1ggeB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding)
1ggeC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding)
1ggeD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding)
1ggfA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128N
1ggfB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128N
1ggfC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128N
1ggfD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128N
1gghA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128A
1gghB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128A
1gghC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128A
1gghD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain ;ASN 201;HIS 392 TYR 415(Heme binding) mutant H128A
1ggjA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;;HIS 392 TYR 415(Heme binding) mutant N201A
1ggjB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;;HIS 392 TYR 415(Heme binding) mutant N201A
1ggjC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;;HIS 392 TYR 415(Heme binding) mutant N201A
1ggjD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;;HIS 392 TYR 415(Heme binding) mutant N201A
1ggkA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;;HIS 392 TYR 415(Heme binding) mutant N201H
1ggkB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;;HIS 392 TYR 415(Heme binding) mutant N201H
1ggkC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;;HIS 392 TYR 415(Heme binding) mutant N201H
1ggkD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;;HIS 392 TYR 415(Heme binding) mutant N201H
1iphA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding)
1iphB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding)
1iphC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding)
1iphD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding)
1p7yA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181A
1p7yB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181A
1p7yC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181A
1p7yD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181A
1p7zA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181S
1p7zB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181S
1p7zC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181S
1p7zD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181S
1p80A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181Q
1p80B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181Q
1p80C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181Q
1p80D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181Q
1p81A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181E
1p81B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181E
1p81C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181E
1p81D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181E
1qf7A01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201; TYR 415(Heme binding) mutant H392Q
1qf7B01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201; TYR 415(Heme binding) mutant H392Q
1qf7C01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201; TYR 415(Heme binding) mutant H392Q
1qf7D01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201; TYR 415(Heme binding) mutant H392Q
1qwsA01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181N
1qwsB01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181N
1qwsC01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181N
1qwsD01 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain HIS 128;ASN 201;HIS 392 TYR 415(Heme binding) mutant D181N
1cf9A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1cf9B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1cf9C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1cf9D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gg9A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gg9B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gg9C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gg9D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggeA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggeB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggeC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggeD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggfA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggfB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggfC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggfD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gghA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gghB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gghC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gghD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggjA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggjB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggjC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggjD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggkA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggkB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggkC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggkD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1iphA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1iphB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1iphC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1iphD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7yA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7yB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7yC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7yD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7zA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7zB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7zC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7zD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p80A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p80B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p80C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p80D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p81A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p81B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p81C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p81D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qf7A02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qf7B02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qf7C02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qf7D02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qwsA02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qwsB02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qwsC02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qwsD02 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1cf9A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1cf9B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1cf9C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1cf9D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gg9A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gg9B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gg9C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gg9D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggeA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggeB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggeC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggeD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggfA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggfB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggfC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggfD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gghA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gghB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gghC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1gghD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggjA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggjB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggjC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggjD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggkA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggkB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggkC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1ggkD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1iphA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1iphB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1iphC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1iphD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7yA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7yB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7yC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7yD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7zA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7zB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7zC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p7zD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p80A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p80B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p80C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p80D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p81A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p81B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p81C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1p81D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qf7A03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qf7B03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qf7C03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qf7D03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qwsA03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qwsB03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qwsC03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain
1qwsD03 Pdbj logo s Rasmollogo id Rasmollogo chain Mmcif id Mmcif chain

References for Catalytic Mechanism
References Sections No. of steps in catalysis
[9]
Fig.6, Fig.7, p.1017-1021
[11]
Fig.6
[17]

References
[1]
Resource
Comments
Medline ID
PubMed ID 2543292
Journal Arch Biochem Biophys
Year 1989
Volume 271
Pages 323-31
Authors Schellhorn HE, Pou S, Moody C, Hassan HM
Title An electron spin resonance study of oxyradical generation in superoxide dismutase- and catalase-deficient mutants of Escherichia coli K-12.
Related PDB
Related UniProtKB
[2]
Resource
Comments
Medline ID
PubMed ID 2187997
Journal J Mol Biol
Year 1990
Volume 213
Pages 219-20
Authors Tormo J, Fita I, Switala J, Loewen PC
Title Crystallization and preliminary X-ray diffraction analysis of catalase HPII from Escherichia coli.
Related PDB
Related UniProtKB
[3]
Resource
Comments
Medline ID
PubMed ID 1662642
Journal FEBS Lett
Year 1991
Volume 295
Pages 123-6
Authors Dawson JH, Bracete AM, Huff AM, Kadkhodayan S, Zeitler CM, Sono M, Chang CK, Loewen PC
Title The active site structure of E. coli HPII catalase. Evidence favoring coordination of a tyrosinate proximal ligand to the chlorin iron.
Related PDB
Related UniProtKB
[4]
Resource
Comments X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS).
Medline ID 95393020
PubMed ID 7663946
Journal Structure
Year 1995
Volume 3
Pages 491-502
Authors Bravo J, Verdaguer N, Tormo J, Betzel C, Switala J, Loewen PC, Fita I
Title Crystal structure of catalase HPII from Escherichia coli.
Related PDB 1iph
Related UniProtKB P21179
[5]
Resource
Comments
Medline ID
PubMed ID 8955627
Journal Gene
Year 1996
Volume 179
Pages 39-44
Authors Loewen P
Title Probing the structure of catalase HPII of Escherichia coli--a review.
Related PDB
Related UniProtKB
[6]
Resource
Comments
Medline ID
PubMed ID 8621527
Journal J Biol Chem
Year 1996
Volume 271
Pages 8863-8
Authors Murshudov GN, Grebenko AI, Barynin V, Dauter Z, Wilson KS, Vainshtein BK, Melik-Adamyan W, Bravo J, Ferran JM, Ferrer JC, Switala J, Loewen PC, Fita I
Title Structure of the heme d of Penicillium vitale and Escherichia coli catalases.
Related PDB
Related UniProtKB
[7]
Resource
Comments
Medline ID
PubMed ID 9185614
Journal Arch Biochem Biophys
Year 1997
Volume 342
Pages 58-67
Authors Obinger C, Maj M, Nicholls P, Loewen P
Title Activity, peroxide compound formation, and heme d synthesis in Escherichia coli HPII catalase.
Related PDB
Related UniProtKB
[8]
Resource
Comments
Medline ID
PubMed ID 9479449
Journal Biochimie
Year 1997
Volume 79
Pages 667-71
Authors Jouve HM, Andreoletti P, Gouet P, Hajdu J, Gagnon J
Title Structural analysis of compound I in hemoproteins: study on Proteus mirabilis catalase.
Related PDB
Related UniProtKB
[9]
Resource
Comments
Medline ID
PubMed ID 9144772
Journal Protein Sci
Year 1997
Volume 6
Pages 1016-23
Authors Bravo J, Fita I, Ferrer JC, Ens W, Hillar A, Switala J, Loewen PC
Title Identification of a novel bond between a histidine and the essential tyrosine in catalase HPII of Escherichia coli.
Related PDB
Related UniProtKB
[10]
Resource
Comments
Medline ID
PubMed ID 9659382
Journal Biochim Biophys Acta
Year 1998
Volume 1384
Pages 209-22
Authors Maj M, Loewen P, Nicholls P
Title E. coli HPII catalase interaction with high spin ligands: formate and fluoride as active site probes.
Related PDB
Related UniProtKB
[11]
Resource
Comments X-ray crystallography
Medline ID
PubMed ID 10488114
Journal J Biol Chem
Year 1999
Volume 274
Pages 27717-25
Authors Mate MJ, Sevinc MS, Hu B, Bujons J, Bravo J, Switala J, Ens W, Loewen PC, Fita I
Title Mutants that alter the covalent structure of catalase hydroperoxidase II from Escherichia coli.
Related PDB 1cf9
Related UniProtKB
[12]
Resource
Comments X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS).
Medline ID 99190072
PubMed ID 10091651
Journal Protein Sci
Year 1999
Volume 8
Pages 490-8
Authors Sevinc MS, Mate MJ, Switala J, Fita I, Loewen PC
Title Role of the lateral channel in catalase HPII of Escherichia coli.
Related PDB
Related UniProtKB P21179
[13]
Resource
Comments
Medline ID
PubMed ID 10022351
Journal Proteins
Year 1999
Volume 34
Pages 155-66
Authors Bravo J, Mate MJ, Schneider T, Switala J, Wilson K, Loewen PC, Fita I
Title Structure of catalase HPII from Escherichia coli at 1.9 A resolution.
Related PDB
Related UniProtKB
[14]
Resource
Comments
Medline ID
PubMed ID 11275470
Journal Free Radic Biol Med
Year 2001
Volume 30
Pages 709-14
Authors Brunelli L, Yermilov V, Beckman JS
Title Modulation of catalase peroxidatic and catalatic activity by nitric oxide.
Related PDB
Related UniProtKB
[15]
Resource
Comments
Medline ID
PubMed ID 11119647
Journal Proteins
Year 2001
Volume 42
Pages 230-6
Authors Horvath MM, Grishin NV
Title The C-terminal domain of HPII catalase is a member of the type I glutamine amidotransferase superfamily.
Related PDB
Related UniProtKB
[16]
Resource
Comments X-RAY CRYSTALLOGRAPHY (1.89 ANGSTROMS).
Medline ID 21348730
PubMed ID 11455600
Journal Proteins
Year 2001
Volume 44
Pages 270-81
Authors Melik-Adamyan W, Bravo J, Carpena X, Switala J, Mate MJ, Fita I, Loewen PC
Title Substrate flow in catalases deduced from the crystal structures of active site variants of HPII from Escherichia coli.
Related PDB 1gg9 1gge 1ggf 1ggh 1ggj 1ggk 1qf7
Related UniProtKB P21179
[17]
Resource
Comments X-ray crystallography
Medline ID
PubMed ID 12777389
Journal J Biol Chem
Year 2003
Volume 278
Pages 31290-6
Authors Chelikani P, Carpena X, Fita I, Loewen PC
Title An electrical potential in the access channel of catalases enhances catalysis.
Related PDB 1p7y 1p7z 1p80 1p81 1qws
Related UniProtKB
[18]
Resource
Comments
Medline ID
PubMed ID 14745498
Journal Cell Mol Life Sci
Year 2004
Volume 61
Pages 192-208
Authors Chelikani P, Fita I, Loewen PC
Title Diversity of structures and properties among catalases.
Related PDB
Related UniProtKB

Comments
There are three types of catalases, which are monofunctional catalases, bifunctional catalase-peroxidases and manganese-containing catalases. This enzyme corresponds to monofunctional catalases.
This enzyme catalyzes the following reactions:
(1) Enzyme(Por-Fe(III)) + H2O2 -> Compound I(Por(+)-Fe(IV)=O) + H2O
(2) Compound I(Por(+)-Fe(IV)=O) + H2O2 -> Enzyme(Por-Fe(III)) + H2O + O2
During catalysis, a covalent bond between the ND o the imidazole ring of His392 and the CB of Tyr415 is formed, according to the literature [9]. Moreover, heme group also self-catalyzes to facilitate spirolactone cyclization (see [9]).

Created Updated
2005-05-19 2009-02-26